Rather than relying on hydration alone, Pickle It is designed to act through this sensory reflex. Research referenced by the brand found that pickle juice shortened the duration of electrically induced cramps compared with water, with the effect occurring too quickly to be explained by fluid or electrolytes reaching the muscle. The evidence is strongest for induced cramp, so Pickle It is positioned for use when cramp starts rather than as a preventative.

Alongside its 0.6% acetic acid content, each 70ml shot provides approximately 301mg potassium, 46mg magnesium and 266mg sodium. Potassium contributes to normal muscle function, while the small 70ml serving makes the shot practical to carry during training and racing without adding a large volume of fluid.

The formula contains just water, spirit vinegar, magnesium potassium citrate, salt and dill flavouring. It contains no sugar, no declarable allergens or additives, and the product is Informed Choice certified for additional reassurance for tested athletes.

Exercise-associated muscle cramp is not thought to be caused by dehydration and electrolyte loss alone. One proposed mechanism is altered neuromuscular control, where motor neurons become overactive and keep the affected muscle contracted. Pickle It uses 0.6% acetic acid to create a strong acidic taste that stimulates TRP receptors in the mouth and throat. This sensory input travels to the brainstem and spinal cord, where it is proposed to dampen the excessive motor neuron activity associated with the cramp.

The effect is designed to happen through this sensory reflex rather than by waiting for electrolytes to be absorbed. Pickle It also provides potassium, magnesium and sodium alongside the acidic shot, with potassium contributing to normal muscle function. The supporting research cited by the brand is strongest for electrically induced cramp, with individual responses varying.