Hereditary Heart Health Test
30 gene test analyses your risk of developing FH and other heart conditions
Test only available to those aged 18 years or above.
Is the Hereditary Heart Health Test right for you?
Most cases of heart disease are due to a combination of lifestyle choices: being overweight, having an unhealthy diet, smoking and drinking can all contribute to your risk.
But for 1 in 200 people, it can have a genetic basis – and knowing if you are one of those people means you can take action early, reducing your risk of developing disease as much as possible.
Want to understand more read the blog; What & Why - Hereditary Heart Health Tests?
Direct from this website:
Step 1: Buy the test
Click the ‘Buy now’ tab above and follow the instructions. You’ll receive a kit in the post with all the paperwork you need to sign and clear instructions on giving your sample
Step 2: Provide a saliva sample
It’s a simple ‘spit test’ that you can do in your own home – we don’t need a blood sample, all we need is your saliva.
Once you have your test kit, open it and read the instructions carefully and use the enclosed tube to provide a saliva sample. Complete Request Form (A), Consent Form (B) and the Health and History Form (C).
Step 3: Send your completed kit back
Post the sample pack at any post box free to: Freepost, BRCAtest uk
Step 4: Reporting
Your sample will be sequenced and your genes analysed. A report will be generated, usually within 3-4 weeks of receipt of your kit in the laboratory.
Getting the Results
As part of the test package you will have access to a Caridologist who will provide counsel if you receive a positive result - Dr Orhan Uzan, consultant cardiologist specialising in congenital heart disease.
If test is negative, this does not mean the person is then at no risk as there may be other complications that this test does not cover. Always contact your GP if you have any questions or concerns.
Many inherited heart conditions can be life-threatening if left undetected and untreated. They include:
- Cardiomyopathy: An abnormality of the heart muscle making it harder for the heart to pump blood to the body
- Arrhythmia: An abnormality of the heart rhythm causing the heart to beat too fast, too slow or irregularly
- Arteriopathy: Problems with the structure of the arteries in many parts of the body, including the heart
- Familial Hypercholesterolemia (FH): Causes very high cholesterol from a young age and makes you more likely to get coronary heart disease.
But knowing you have increased risk of developing these conditions can help you and your healthcare provider create a personalised plan – such as regular monitoring of your heart’s rhythm or cholesterol-lowering medications – to prevent heart disease or sudden cardiac arrest.
For your family
This information can help your family, too – because inherited heart conditions can run in families, knowing whether you’re at risk can help your loved ones take proactive care of their own heart health. For example, if you have an inherited heart condition, there’s a 50% chance that each of your parents, children, brothers and sisters, will also have it. Finding out early and getting appropriate treatment can help your loved ones understand their risk of coronary heart disease and make sure they get the advice and healthcare they need.
What your results mean for you
Most people receive a negative result.
This means no mutations associated with the 30 genes analyzed were identified. Not all genes covering the listed conditions are tested. It’s important to share your results with your provider to create a personalized healthcare plan.
A small percentage of people receive a positive result.
This means a mutation associated with the 30 genes analyzed was identified. It’s important to share your results with your provider to create a personalized healthcare plan.
It’s normal to find variants of uncertain significance.
It is common to see genetic changes that require further research to determine whether they are associated with an increased risk for develop inherited heart conditions. Most are eventually found to be harmless; we’ll try to contact you if their classification changes.
Additional evaluations may be recommended based on your health history.
If you have a personal or family history of specific heart conditions, additional evaluations by a cardiologist may be recommended.
Heart conditions can be affected by many factors.
Even if your results show no mutations, you may still develop an inherited heart condition. While Color’s Hereditary Heart Health Test looks at 30 genes associated with inherited heart conditions that have actionable treatment plans, factors like lifestyle, environment, and mutations in other genes not covered in the test, may increase the risk for these and other heart conditions as well.
A positive result does not mean that you will develop an inherited heart condition.
Not everyone with a mutation in one of these genes has or will develop an inherited heart condition. But knowing you have a mutation can help your healthcare provider make tailored recommendations.
This test is provided by Color distributed in the UK by Everything Genetics Ltd